2AHX
Crystal structure of ErbB4/HER4 extracellular domain
Summary for 2AHX
Entry DOI | 10.2210/pdb2ahx/pdb |
Descriptor | Receptor tyrosine-protein kinase erbB-4, 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ... (5 entities in total) |
Functional Keywords | x-ray crystallography; neuregulins; heparin-binding, cell cycle, signaling protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 141978.14 |
Authors | Bouyain, S.,Longo, P.A.,Li, S.,Ferguson, K.M.,Leahy, D.J. (deposition date: 2005-07-28, release date: 2005-09-27, Last modification date: 2020-07-29) |
Primary citation | Bouyain, S.,Longo, P.A.,Li, S.,Ferguson, K.M.,Leahy, D.J. The extracellular region of ErbB4 adopts a tethered conformation in the absence of ligand Proc.Natl.Acad.Sci.USA, 102:15024-15029, 2005 Cited by PubMed: 16203964DOI: 10.1073/pnas.0507591102 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.396 Å) |
Structure validation
Download full validation report