1YYL

crystal structure of CD4M33, a scorpion-toxin mimic of CD4, in complex with HIV-1 YU2 gp120 envelope glycoprotein and anti-HIV-1 antibody 17b

Summary for 1YYL

• Entry DOI: 10.2210/pdb1yyl/pdb
• Related: 1YYM
• Descriptor: Exterior membrane glycoprotein(GP120),Exterior membrane glycoprotein(GP120),Exterior membrane glycoprotein(GP120), antibody 17b light chain, antibody 17b heavy chain, ... (6 entities in total)
• Functional Keywords: hiv-1, gp120, yu2, scorpion toxin, cd4 mimic, cd4m33, antibody, viral protein-immune system complex, viral protein/immune system
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 8
• Total formula weight: 174810.55

Authors

Huang, C.C.,Stricher, F.,Martin, L.,Decker, J.M.,Majeed, S.,Barthe, P.,Hendrickson, W.A.,Robinson, J.,Roumestand, C.,Sodroski, J.,Wyatt, R.,Shaw, G.M.,Vita, C.,Kwong, P.D. (deposition date: 2005-02-25, release date: 2005-05-03, Last modification date: 2023-10-25)

• Primary citation: Huang, C.C.,Stricher, F.,Martin, L.,Decker, J.M.,Majeed, S.,Barthe, P.,Hendrickson, W.A.,Robinson, J.,Roumestand, C.,Sodroski, J.,Wyatt, R.,Shaw, G.M.,Vita, C.,Kwong, P.D.; Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus gp120 crystal structures, molecular mimicry, and neutralization breadth.; Structure, 13:755-768, 2005; PubMed: 15893666; DOI: 10.1016/j.str.2005.03.006

Experimental method

X-RAY DIFFRACTION (2.75 Å)