1YQR

Catalytically inactive human 8-oxoguanine glycosylase crosslinked to oxoG containing DNA

Summary for 1YQR

• Entry DOI: 10.2210/pdb1yqr/pdb
• Related: 1EBM 1YQK 1YQL 1YQM
• Descriptor: 5'-D(P*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*G)-3', 5'-D(P*CP*GP*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3', N-glycosylase/DNA lyase, ... (5 entities in total)
• Functional Keywords: disulfide crosslinking, crosslinking validation, hydrolase-dna complex, hydrolase/dna
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus, nucleoplasm . Isoform 1A: Nucleus. Isoform 2A: Mitochondrion: O15527
• Total number of polymer chains: 3
• Total formula weight: 44629.42

Authors

Banerjee, A.,Yang, W.,Karplus, M.,Verdine, G.L. (deposition date: 2005-02-02, release date: 2005-04-05, Last modification date: 2024-02-14)

• Primary citation: Banerjee, A.,Yang, W.,Karplus, M.,Verdine, G.L.; Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA.; Nature, 434:612-618, 2005; PubMed: 15800616; DOI: 10.1038/nature03458

Experimental method

X-RAY DIFFRACTION (2.43 Å)