1YCM

Solution Structure of matrix metalloproteinase 12 (MMP12) in the presence of N-Isobutyl-N-[4-methoxyphenylsulfonyl]glycyl hydroxamic acid (NNGH)

1YCM の概要

• エントリーDOI: 10.2210/pdb1ycm/pdb
• NMR情報: BMRB: 6444
• 分子名称: Macrophage metalloelastase, ZINC ION, CALCIUM ION, ... (4 entities in total)
• 機能のキーワード: macrophage metalloelastase, mmp-12, solution structure, nngh, zinc, calcium, structural proteomics in europe, spine, structural genomics, hydrolase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Secreted, extracellular space, extracellular matrix (Probable): P39900
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 18183.09

構造登録者

Bertini, I.,Calderone, V.,Cosenza, M.,Fragai, M.,Lee, Y.M.,Luchinat, C.,Mangani, S.,Terni, B.,Turano, P.,Structural Proteomics in Europe (SPINE) (登録日: 2004-12-22, 公開日: 2005-04-19, 最終更新日: 2021-10-20)

• 主引用文献: Bertini, I.,Calderone, V.,Cosenza, M.,Fragai, M.,Lee, Y.M.,Luchinat, C.,Mangani, S.,Terni, B.,Turano, P.; Conformational variability of matrix metalloproteinases: Beyond a single 3D structure.; Proc.Natl.Acad.Sci.Usa, 102:5334-5339, 2005; PubMed: 15809432; DOI: 10.1073/pnas.0407106102

実験手法

SOLUTION NMR