1Y4L

Crystal structure of Bothrops asper myotoxin II complexed with the anti-trypanosomal drug suramin

Summary for 1Y4L

• Entry DOI: 10.2210/pdb1y4l/pdb
• Related: 1CLP
• Descriptor: Phospholipase A2 homolog 2, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ISOPROPYL ALCOHOL, ... (5 entities in total)
• Functional Keywords: bothrops asper myotoxin ii, anti-trypanosomal drug suramin, hydrolase
• Biological source: Bothrops asper (terciopelo)
• Cellular location: Secreted: P24605
• Total number of polymer chains: 2
• Total formula weight: 29778.80

Authors

Murakami, M.T.,Arruda, E.Z.,Melo, P.A.,Martinez, A.B.,Calil-Elias, S.,Tomaz, M.A.,Lomonte, B.,Gutierrez, J.M.,Arni, R.K. (deposition date: 2004-12-01, release date: 2005-06-28, Last modification date: 2017-10-11)

• Primary citation: Murakami, M.T.,Arruda, E.Z.,Melo, P.A.,Martinez, A.B.,Calil-Elias, S.,Tomaz, M.A.,Lomonte, B.,Gutierrez, J.M.,Arni, R.K.; Inhibition of Myotoxic Activity of Bothrops asper Myotoxin II by the Anti-trypanosomal Drug Suramin.; J.Mol.Biol., 350:416-426, 2005; PubMed: 15961104; DOI: 10.1016/j.jmb.2005.04.072

Experimental method

X-RAY DIFFRACTION (1.7 Å)