1Y2G

Crystal STructure of ZipA in complex with an inhibitor

Summary for 1Y2G

• Entry DOI: 10.2210/pdb1y2g/pdb
• Related: 1Y2F
• Descriptor: Cell division protein zipA, N-METHYL-N-[3-(6-PHENYL[1,2,4]TRIAZOLO[4,3-B]PYRIDAZIN-3-YL)PHENYL]ACETAMIDE (3 entities in total)
• Functional Keywords: cell cycle
• Biological source: Escherichia coli
• Cellular location: Cell inner membrane; Single-pass type I membrane protein: P77173
• Total number of polymer chains: 2
• Total formula weight: 31669.08

Authors

Mosyak, L.,Rush, T.S. (deposition date: 2004-11-22, release date: 2005-03-01, Last modification date: 2023-08-23)

• Primary citation: Rush, T.S.,Grant, J.A.,Mosyak, L.,Nicholls, A.; A shape-based 3-D scaffold hopping method and its application to a bacterial protein-protein interaction; J.Med.Chem., 48:1489-1495, 2005; PubMed: 15743191; DOI: 10.1021/jm040163o

Experimental method

X-RAY DIFFRACTION (1.9 Å)