1Y0S

Crystal structure of PPAR delta complexed with GW2331

Summary for 1Y0S

• Entry DOI: 10.2210/pdb1y0s/pdb
• Descriptor: Peroxisome proliferator activated receptor delta, IODIDE ION, (2S)-2-(4-[2-(3-[2,4-DIFLUOROPHENYL]-1-HEPTYLUREIDO)ETHYL]PHENOXY)-2-METHYLBUTYRIC ACID, ... (5 entities in total)
• Functional Keywords: ppar, hormone-growth factor receptor complex, hormone/growth factor receptor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 65162.15

Authors

Takada, I.,Yu, R.T.,Xu, H.E.,Xu, R.X.,Lambert, M.H.,Montana, V.G.,Kliewer, S.A.,Evans, R.M.,Umesono, K. (deposition date: 2004-11-16, release date: 2005-03-29, Last modification date: 2023-08-23)

• Primary citation: Takada, I.,Yu, R.T.,Xu, H.E.,Lambert, M.H.,Montana, V.G.,Kliewer, S.A.,Evans, R.M.,Umesono, K.; Alteration of a Single Amino Acid in Peroxisome Proliferator-Activated Receptor-alpha (PPARalpha) Generates a PPAR delta Phenotype; MOL.ENDOCRINOL., 14:733-740, 2000; PubMed: 10809235; DOI: 10.1210/me.14.5.733

Experimental method

X-RAY DIFFRACTION (2.65 Å)