1XT3

Structure Basis of Venom Citrate-Dependent Heparin Sulfate-Mediated Cell Surface Retention of Cobra Cardiotoxin A3

Summary for 1XT3

Entry DOI	10.2210/pdb1xt3/pdb
Descriptor	Cytotoxin 3, 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, CITRIC ACID, ... (4 entities in total)
Functional Keywords	ctx-3, heparin, citrate, toxin
Biological source	Naja atra (Chinese cobra)
Cellular location	Secreted : P60301
Total number of polymer chains	2
Total formula weight	15459.21
Authors	Lee, S.-C.,Guan, H.-H.,Wang, C.-H.,Huang, W.-N.,Chen, C.-J.,Wu, W.-G. (deposition date: 2004-10-21, release date: 2004-12-14, Last modification date: 2020-07-29)
Primary citation	Lee, S.-C.,Guan, H.-H.,Wang, C.-H.,Huang, W.-N.,Tjong, S.-C.,Chen, C.-J.,Wu, W.-G. Structural basis of citrate-dependent and heparan sulfate-mediated cell surface retention of cobra cardiotoxin A3 J.Biol.Chem., 280:9567-9577, 2005 Cited by PubMed: 15590643 DOI: 10.1074/jbc.M412398200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation