1X27
Crystal Structure of Lck SH2-SH3 with SH2 binding site of p130Cas
Summary for 1X27
Entry DOI | 10.2210/pdb1x27/pdb |
Related | 1lck |
Descriptor | Proto-oncogene tyrosine-protein kinase LCK, CRK-associated substrate, SODIUM ION, ... (4 entities in total) |
Functional Keywords | lck-cas complex, lck phospho-peptide complex, high affinity lck-cas complex, signaling protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P06239 Cell junction, focal adhesion: Q63767 |
Total number of polymer chains | 12 |
Total formula weight | 121003.40 |
Authors | Nasertorabi, F.,Tars, K.,Becherer, K.,Kodandapani, R.,Liljas, L.,Vuori, K.,Ely, K.R. (deposition date: 2005-04-20, release date: 2006-02-07, Last modification date: 2023-11-15) |
Primary citation | Nasertorabi, F.,Tars, K.,Becherer, K.,Kodandapani, R.,Liljas, L.,Vuori, K.,Ely, K.R. Molecular basis for regulation of Src by the docking protein p130Cas J.MOL.RECOG., 19:30-38, 2006 Cited by PubMed: 16245368DOI: 10.1002/jmr.755 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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