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1UYI

Human Hsp90-alpha with 8-(2,5-dimethoxy-benzyl)-2-fluoro-9-pent-9H-purin-6-ylamine

Summary for 1UYI
Entry DOI10.2210/pdb1uyi/pdb
Related1BYQ 1OSF 1UY6 1UY7 1UY8 1UY9 1UYC 1UYD 1UYE 1UYF 1UYG 1UYH 1UYK 1UYL 1UYM 1YER 1YES 1YET
DescriptorHEAT SHOCK PROTEIN HSP 90-ALPHA, 8-(2,5-DIMETHOXY-BENZYL)-2-FLUORO-9-PENT-9H-PURIN-6-YLAMINE (3 entities in total)
Functional Keywordshsp90, atpase, puz, chaperone, atp-binding, heat shock
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCytoplasm : P07900
Total number of polymer chains1
Total formula weight26980.20
Authors
Primary citationWright, L.,Barril, X.,Dymock, B.,Sheridan, L.,Surgenor, A.,Beswick, M.,Drysdale, M.,Collier, A.,Massey, A.,Davies, N.,Fink, A.,Fromont, C.,Aherne, W.,Boxall, K.,Sharp, S.,Workman, P.,Hubbard, R.E.
Structure-Activity Relationships in Purine-Based Inhibitor Binding to Hsp90 Isoforms
Chem.Biol., 11:775-, 2004
Cited by
PubMed: 15217611
DOI: 10.1016/J.CHEMBIOL.2004.03.033
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

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