1UV5

GLYCOGEN SYNTHASE KINASE 3 BETA COMPLEXED WITH 6-BROMOINDIRUBIN-3'-OXIME

Summary for 1UV5

Entry DOI	10.2210/pdb1uv5/pdb
Related	1GNG 1H8F 1I09 1J1B 1J1C 1O6K 1O6L 1O9U 1PYX 1Q3D 1Q3W 1Q41 1Q4L
Descriptor	GLYCOGEN SYNTHASE KINASE-3 BETA, 6-BROMOINDIRUBIN-3'-OXIME, PHOSPHATE ION, ... (6 entities in total)
Functional Keywords	transferase, kinase, insulin pathway, wnt signaling pathway, transferase serine/threonine-protein kinase
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Cytoplasm: P49841
Total number of polymer chains	1
Total formula weight	40299.14
Authors	Dajani, R.,Pearl, L.H.,Roe, S.M. (deposition date: 2004-01-14, release date: 2004-01-29, Last modification date: 2023-12-13)
Primary citation	Meijer, L.,Skaltsounis, A.-L.,Magiatis, P.,Polychronopoulous, P.,Knockaert, M.,Leost, M.,Ryan, X.P.,Vonica, C.A.,Brivanlou, A.,Dajani, R.,Crovace, C.,Tarricone, C.,Musacchio, A.,Roe, S.M.,Pearl, L.H.,Greengard, P. Gsk-3-Selective Inhibitors Derived from Tyrian Purple Indurubins Chem.Biol., 10:1255-, 2003 Cited by PubMed: 14700633 DOI: 10.1016/J.CHEMBIOL.2003.11.010 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation