1UNJ

Crystal structure of a 7-Aminoactinomycin D complex with non-complementary DNA

Summary for 1UNJ

• Entry DOI: 10.2210/pdb1unj/pdb
• Related: 173D 1A7Y 1A7Z 1DSC 1DSD 1FJA 1I3W 1L1V 1MNV 1OVF 1QFI 1UNM 209D 2D55 316D
• Related PRD ID: PRD_000010
• Descriptor: 5'-D(*TP*TP*AP*GP*BRU*TP)-3', 7-AMINO-ACTINOMYCIN D (3 entities in total)
• Functional Keywords: actinomycin d, actinomycin, antibiotic, anti cancer, antitumor, chromophore, depsipeptide, dna-antibiotic complex, fluorescent agent, hoogsten base-pair, dna/antibiotic
• Biological source: STREPTOMYCES ANTIBIOTICUS
• Total number of polymer chains: 24
• Total formula weight: 40261.23

Authors

Alexopoulos, E.C.,Klement, R.,Jares-Erijman, E.A.,Uson, I.,Jovin, T.M.,Sheldrick, G.M. (deposition date: 2003-09-10, release date: 2004-12-16, Last modification date: 2023-11-15)

• Primary citation: Alexopoulos, E.C.,Jares-Erijman, E.A.,Jovin, T.M.,Klement, R.,Machinek, R.,Sheldrick, G.M.,Uson, I.; Crystal and Solution Structures of 7-Amino-Actinomycin D Complexes with D(Ttagbrut), D(Ttagtt) and D(Tttagttt); Acta Crystallogr.,Sect.D, 61:407-, 2005; PubMed: 15805595; DOI: 10.1107/S090744490500082X

Experimental method

X-RAY DIFFRACTION (2.5 Å)