1UA1
Structure of aminofluorene adduct paired opposite cytosine at the polymerase active site.
Summary for 1UA1
| Entry DOI | 10.2210/pdb1ua1/pdb |
| Related | 1UA0 |
| Descriptor | DNA primer strand, DNA template strand with aminofluorene adduct, DNA polymerase I, ... (6 entities in total) |
| Functional Keywords | dna polymerase i; dna replication; klenow fragment; protein-dna complex; aminofluorene; aromatic amine; dna lesion; translation replication, transferase-dna complex, transferase/dna |
| Biological source | Geobacillus stearothermophilus |
| Total number of polymer chains | 3 |
| Total formula weight | 74199.14 |
| Authors | Hsu, G.W.,Kiefer, J.R.,Becherel, O.J.,Fuchs, R.P.P.,Beese, L.S. (deposition date: 2004-08-11, release date: 2004-09-28, Last modification date: 2024-02-14) |
| Primary citation | Hsu, G.W.,Kiefer, J.R.,Becherel, O.J.,Fuchs, R.P.P.,Beese, L.S. Observing translesion synthesis of an aromatic amine DNA adduct by a high-fidelity DNA polymerase J.Biol.Chem., 279:50280-50285, 2004 Cited by PubMed: 15385534DOI: 10.1074/jbc.M409224200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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