1TWG

RNA polymerase II complexed with CTP

Summary for 1TWG

Entry DOI	10.2210/pdb1twg/pdb
Related	1twa 1twc 1twf 1twh
Descriptor	DNA-directed RNA polymerase II largest subunit, DNA-directed RNA polymerases I, II, and III 7.7 kDa polypeptide, MANGANESE (II) ION, ... (14 entities in total)
Functional Keywords	transcription, mrna, multiprotein complex, molecular machine, zinc motifs
Biological source	Saccharomyces cerevisiae (baker's yeast) More
Cellular location	Nucleus: P04050 P08518 P16370 P20434 P20436 P27999 P38902 Nucleus, nucleolus: P40422 P22139 Cytoplasm: P20435
Total number of polymer chains	10
Total formula weight	470742.28
Authors	Westover, K.D.,Bushnell, D.A.,Kornberg, R.D. (deposition date: 2004-06-30, release date: 2004-11-16, Last modification date: 2023-08-23)
Primary citation	Westover, K.D.,Bushnell, D.A.,Kornberg, R.D. Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center. Cell(Cambridge,Mass.), 119:481-489, 2004 Cited by PubMed: 15537538 DOI: 10.1016/j.cell.2004.10.016 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.3 Å)

Structure validation