1TVY

beta-1,4-galactosyltransferase mutant Met344His (M344H-Gal-T1) complex with UDP-galactose and manganese

Summary for 1TVY

Related1O0R 1TW1 1TW5
DescriptorBeta-1,4-galactosyltransferase 1, GALACTOSE-URIDINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... (6 entities in total)
Functional Keywordsmet344his mutantion; closed conformation; mn binding, transferase
Biological sourceBos taurus (cattle)
Cellular locationIsoform Long: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Isoform Short: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Processed beta-1,4-galactosyltransferase 1: Secreted P08037
Total number of polymer chains2
Total molecular weight67823.22
Authors
Ramakrishnan, B.,Boeggeman, E.,Qasba, P.K. (deposition date: 2004-06-30, release date: 2004-12-14, Last modification date: 2011-07-13)
Primary citation
Ramakrishnan, B.,Boeggeman, E.,Qasba, P.K.
Effect of the Met344His mutation on the conformational dynamics of bovine beta-1,4-galactosyltransferase: crystal structure of the Met344His mutant in complex with chitobiose
Biochemistry, 43:12513-12522, 2004
PubMed: 15449940 (PDB entries with the same primary citation)
DOI: 10.1021/bi049007+
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.3 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2401505.9%3.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution