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1TVW

CONTRIBUTIONS OF ORIENTATION AND HYDROGEN BONDING TO CATALYSIS IN ASN-229 MUTANTS OF THYMIDYLATE SYNTHASE

Summary for 1TVW
Entry DOI10.2210/pdb1tvw/pdb
DescriptorTHYMIDYLATE SYNTHASE, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, ... (4 entities in total)
Functional Keywordstransferase, methyltransferase
Biological sourceLactobacillus casei
Cellular locationCytoplasm: P00469
Total number of polymer chains1
Total formula weight37389.08
Authors
Finer-Moore, J.,Stroud, R.M. (deposition date: 1997-09-17, release date: 1998-01-28, Last modification date: 2024-02-14)
Primary citationFiner-Moore, J.S.,Liu, L.,Birdsall, D.L.,Brem, R.,Apfeld, J.,Santi, D.V.,Stroud, R.M.
Contributions of orientation and hydrogen bonding to catalysis in Asn229 mutants of thymidylate synthase.
J.Mol.Biol., 276:113-129, 1998
Cited by
PubMed: 9514716
DOI: 10.1006/jmbi.1997.1495
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

217705

數據於2024-03-27公開中

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