1TT5

Structure of APPBP1-UBA3-Ubc12N26: a unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8

Summary for 1TT5

Entry DOI	10.2210/pdb1tt5/pdb
Descriptor	amyloid protein-binding protein 1, ubiquitin-activating enzyme E1C isoform 1, Ubiquitin-conjugating enzyme E2 M, ... (5 entities in total)
Functional Keywords	cell cycle, ligase
Biological source	Homo sapiens (human) More
Total number of polymer chains	6
Total formula weight	223428.73
Authors	Huang, D.T.,Miller, D.W.,Mathew, R.,Cassell, R.,Holton, J.M.,Roussel, M.F.,Schulman, B.A. (deposition date: 2004-06-21, release date: 2004-09-14, Last modification date: 2024-02-14)
Primary citation	Huang, D.T.,Miller, D.W.,Mathew, R.,Cassell, R.,Holton, J.M.,Roussel, M.F.,Schulman, B.A. A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8. Nat.Struct.Mol.Biol., 11:927-935, 2004 Cited by PubMed: 15361859 DOI: 10.1038/nsmb826 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation