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1TOZ

NMR structure of the human NOTCH-1 ligand binding region

Summary for 1TOZ
Entry DOI10.2210/pdb1toz/pdb
Related1EMO 1HJ7 1LMJ
DescriptorNeurogenic locus notch homolog protein 1 (1 entity in total)
Functional Keywordsnotch, egf, calcium binding, ligand binding, module, signaling protein
Biological sourceHomo sapiens (human)
Cellular locationCell membrane; Single-pass type I membrane protein (By similarity). Notch 1 intracellular domain: Nucleus (By similarity): P46531
Total number of polymer chains1
Total formula weight12600.01
Authors
Hambleton, S.,Valeyev, N.Y.,Muranyi, A.,Knott, V.,Werner, J.M.,Mcmichael, A.J.,Handford, P.A.,Downing, A.K. (deposition date: 2004-06-15, release date: 2004-10-12, Last modification date: 2021-11-10)
Primary citationHambleton, S.,Valeyev, N.V.,Muranyi, A.,Knott, V.,Werner, J.M.,McMichael, A.J.,Handford, P.A.,Downing, A.K.
Structural and functional properties of the human notch-1 ligand binding region
STRUCTURE, 12:2173-2183, 2004
Cited by
PubMed: 15576031
DOI: 10.1016/j.str.2004.09.012
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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