1TI7

CRYSTAL STRUCTURE OF NMRA, A NEGATIVE TRANSCRIPTIONAL REGULATOR, IN COMPLEX WITH NADP AT 1.7A RESOLUTION

Replaces:  1PDS

Summary for 1TI7

• Entry DOI: 10.2210/pdb1ti7/pdb
• Descriptor: nitrogen metabolite repression regulator NmrA, POTASSIUM ION, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: rossmann fold, transcriptional regulation, short chain, dehydrogenase, reductase, nadp binding, nmra, transcription
• Biological source: Emericella nidulans
• Total number of polymer chains: 1
• Total formula weight: 40149.85

Authors

Lamb, H.K.,Leslie, K.,Dodds, A.L.,Nutley, M.,Cooper, A.,Johnson, C.,Thompson, P.,Stammers, D.K.,Hawkins, A.R. (deposition date: 2004-06-02, release date: 2004-06-08, Last modification date: 2023-08-23)

• Primary citation: Lamb, H.K.,Leslie, K.,Dodds, A.L.,Nutley, M.,Cooper, A.,Johnson, C.,Thompson, P.,Stammers, D.K.,Hawkins, A.R.; The negative transcriptional regulator NmrA discriminates between oxidized and reduced dinucleotides.; J.Biol.Chem., 278:32107-32114, 2003; PubMed: 12764138; DOI: 10.1074/jbc.M304104200

Experimental method

X-RAY DIFFRACTION (1.7 Å)