1TFC
CRYSTAL STRUCTURE OF THE LIGAND-BINDING DOMAIN OF THE ESTROGEN-RELATED RECEPTOR GAMMA IN COMPLEX WITH A STEROID RECEPTOR COACTIVATOR-1 PEPTIDE
Summary for 1TFC
Entry DOI | 10.2210/pdb1tfc/pdb |
Related | 1KV6 1S9P 1S9Q |
Descriptor | Estrogen-related receptor gamma, steroid receptor coactivator-1 (3 entities in total) |
Functional Keywords | transcriptionally active conformation in absence of ligand, transcription |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus (Probable): P62508 Nucleus (By similarity): Q15788 |
Total number of polymer chains | 4 |
Total formula weight | 60326.03 |
Authors | Greschik, H.,Flaig, R.,Renaud, J.P.,Moras, D. (deposition date: 2004-05-27, release date: 2004-07-27, Last modification date: 2023-08-23) |
Primary citation | Greschik, H.,Flaig, R.,Renaud, J.P.,Moras, D. Structural Basis for the Deactivation of the Estrogen-related Receptor {gamma} by Diethylstilbestrol or 4-Hydroxytamoxifen and Determinants of Selectivity. J.Biol.Chem., 279:33639-33646, 2004 Cited by PubMed: 15161930DOI: 10.1074/jbc.M402195200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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