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1TDW

Crystal structure of double truncated human phenylalanine hydroxylase BH4-responsive PKU mutant A313T.

Summary for 1TDW
Entry DOI10.2210/pdb1tdw/pdb
Related1PAH
DescriptorPhenylalanine-4-hydroxylase, FE (III) ION (3 entities in total)
Functional Keywordsphenylalanine catabolism, oxidoreductase
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight35786.39
Authors
Erlandsen, H.,Pey, A.L.,Gamez, A.,Perez, B.,Desviat, L.R.,Aguado, C.,Koch, R.,Surendran, S.,Tyring, S.,Matalon, R.,Scriver, C.R.,Ugarte, M.,Martinez, A.,Stevens, R.C. (deposition date: 2004-05-24, release date: 2004-11-30, Last modification date: 2023-08-23)
Primary citationErlandsen, H.,Pey, A.L.,Gamez, A.,Perez, B.,Desviat, L.R.,Aguado, C.,Koch, R.,Surendran, S.,Tyring, S.,Matalon, R.,Scriver, C.R.,Ugarte, M.,Martinez, A.,Stevens, R.C.
Correction of kinetic and stability defects by tetrahydrobiopterin in phenylketonuria patients with certain phenylalanine hydroxylase mutations.
Proc.Natl.Acad.Sci.Usa, 101:16903-16908, 2004
Cited by
PubMed: 15557004
DOI: 10.1073/pnas.0407256101
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

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