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1TB6

2.5A Crystal Structure of the Antithrombin-Thrombin-Heparin Ternary Complex

Summary for 1TB6
Entry DOI10.2210/pdb1tb6/pdb
Descriptorthrombin, Antithrombin-III, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
Functional Keywordsheparin, hydrolase-blood clotting complex, hydrolase/blood clotting
Biological sourceHomo sapiens (human)
More
Total number of polymer chains3
Total formula weight92162.06
Authors
Li, W.,Johnson, D.J.,Esmon, C.T.,Huntington, J.A. (deposition date: 2004-05-19, release date: 2004-08-17, Last modification date: 2023-08-23)
Primary citationLi, W.,Johnson, D.J.,Esmon, C.T.,Huntington, J.A.
Structure of the antithrombin-thrombin-heparin ternary complex reveals the antithrombotic mechanism of heparin.
Nat.Struct.Mol.Biol., 11:857-862, 2004
Cited by
PubMed: 15311269
DOI: 10.1038/nsmb811
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

217705

數據於2024-03-27公開中

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