1SZR

A Dimer interface mutant of ornithine decarboxylase reveals structure of gem diamine intermediate

Summary for 1SZR

Entry DOI	10.2210/pdb1szr/pdb
Related	1D7K 1F3T 1NJJ 1QU4 2tod 7ODC
Descriptor	Ornithine decarboxylase, PYRIDOXINE-5'-PHOSPHATE, N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], ... (5 entities in total)
Functional Keywords	pyridoxal phosphate, pxp, odc, ornithine decarboxylase, lyase, gem-diamine, carbinolamine, dimer interface, beta-alpha-barrels, greek key
Biological source	Trypanosoma brucei brucei
Total number of polymer chains	4
Total formula weight	189185.26
Authors	Jackson, L.K.,Baldwin, J.,Goldsmith, E.J.,Phillips, M.A. (deposition date: 2004-04-06, release date: 2004-10-26, Last modification date: 2023-08-23)
Primary citation	Jackson, L.K.,Baldwin, J.,Akella, R.,Goldsmith, E.J.,Phillips, M.A. Multiple active site conformations revealed by distant site mutation in ornithine decarboxylase Biochemistry, 43:12990-12999, 2004 Cited by PubMed: 15476392 DOI: 10.1021/bi048933l PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation