1SIO

Structure of Kumamolisin-As complexed with a covalently-bound inhibitor, AcIPF

Summary for 1SIO

• Entry DOI: 10.2210/pdb1sio/pdb
• Related: 1SIU
• Related PRD ID: PRD_000240
• Descriptor: kumamolisin-As, Ace-ILE-PRO-PHL peptide inhibitor, SULFATE ION, ... (5 entities in total)
• Functional Keywords: kumamolisin-as, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Alicyclobacillus sendaiensis; More
• Total number of polymer chains: 6
• Total formula weight: 111726.05

Authors

Li, M.,Wlodawer, A.,Gustchina, A.,Tsuruoka, N.,Ashida, M.,Minakata, H.,Oyama, H.,Oda, K.,Nishino, T.,Nakayama, T. (deposition date: 2004-03-01, release date: 2004-03-30, Last modification date: 2023-08-23)

• Primary citation: Wlodawer, A.,Li, M.,Gustchina, A.,Tsuruoka, N.,Ashida, M.,Minakata, H.,Oyama, H.,Oda, K.,Nishino, T.,Nakayama, T.; Crystallographic and biochemical investigations of kumamolisin-As, a serine-carboxyl peptidase with collagenase activity; J.Biol.Chem., 279:21500-21510, 2004; PubMed: 15014068; DOI: 10.1074/jbc.M401141200

Experimental method

X-RAY DIFFRACTION (1.8 Å)