1S5Q

Solution Structure of Mad1 SID-mSin3A PAH2 Complex

Summary for 1S5Q

• Entry DOI: 10.2210/pdb1s5q/pdb
• Related: 1G1E 1S5R
• NMR Information: BMRB: 4635
• Descriptor: MAD protein, Sin3a protein (2 entities in total)
• Functional Keywords: protein-peptide complex, amphipathic helix motif, four-helix bundle, repressor-corepressor complex, transcription
• Biological source: Mus musculus (house mouse); More
• Cellular location: Nucleus: Q05195 Q60520
• Total number of polymer chains: 2
• Total formula weight: 12311.74

Authors

Swanson, K.A.,Knoepfler, P.S.,Huang, K.,Kang, R.S.,Cowley, S.M.,Laherty, C.D.,Eisenman, R.N.,Radhakrishnan, I. (deposition date: 2004-01-21, release date: 2004-07-06, Last modification date: 2022-03-02)

• Primary citation: Swanson, K.A.,Knoepfler, P.S.,Huang, K.,Kang, R.S.,Cowley, S.M.,Laherty, C.D.,Eisenman, R.N.,Radhakrishnan, I.; HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations.; Nat.Struct.Mol.Biol., 11:738-746, 2004; PubMed: 15235594; DOI: 10.1038/nsmb798

Experimental method

SOLUTION NMR