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1S4F

Crystal Structure of RNA-dependent RNA polymerase construct 2 from bovine viral diarrhea virus (BVDV)

Summary for 1S4F
Entry DOI10.2210/pdb1s4f/pdb
Related1S48 1S49
DescriptorRNA-dependent RNA polymerase (1 entity in total)
Functional Keywordspolymerase, rna synthesis, primer independent initiation, de novo initiation, bovine viral diarrhea virus, bvdv, replication, rna binding protein
Biological sourceBovine viral diarrhea virus 1
Cellular locationE(rns) glycoprotein: Host membrane; Peripheral membrane protein. Envelope glycoprotein E2: Host cell surface. Cysteine protease NS2: Host membrane; Multi- pass membrane protein (Potential): P19711
Total number of polymer chains4
Total formula weight275787.28
Authors
Choi, K.H.,Groarke, J.M.,Young, D.C.,Kuhn, R.J.,Smith, J.L.,Pevear, D.C.,Rossmann, M.G. (deposition date: 2004-01-16, release date: 2004-04-06, Last modification date: 2011-07-13)
Primary citationChoi, K.H.,Groarke, J.M.,Young, D.C.,Kuhn, R.J.,Smith, J.L.,Pevear, D.C.,Rossmann, M.G.
The structure of the RNA-dependent RNA polymerase from bovine viral diarrhea virus establishes the role of GTP in de novo initiation.
Proc.Natl.Acad.Sci.Usa, 101:4425-4430, 2004
Cited by
PubMed: 15070734
DOI: 10.1073/pnas.0400660101
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3 Å)
Structure validation

217705

數據於2024-03-27公開中

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