1RZG

Crystal structure of Human anti-HIV-1 GP120 reactive antibody 412d

1RZG の概要

関連するPDBエントリー1RZ7 1RZ8 1RZF 1RZI 1RZJ 1RZK
分子名称Fab 412d light chain, Fab 412d heavy chain, SUCROSE, ... (6 entities in total)
機能のキーワードhiv-1; gp120; cd4i; antibodies; tyrosine sulfation; vh-gene usage, immune system
由来する生物種Homo sapiens (human)
ポリマー鎖数4
分子量合計99135.71
構造登録者
主引用文献
Huang, C.C.,Venturi, M.,Majeed, S.,Moore, M.J.,Phogat, S.,Zhang, M.-Y.,Dimitrov, D.S.,Hendrickson, W.A.,Robinson, J.,Sodroski, J.,Wyatt, R.,Choe, H.,Farzan, M.,Kwong, P.D.
Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Proc.Natl.Acad.Sci.USA, 101:2706-2711, 2004
PubMed: 14981267 (主引用文献が同じPDBエントリー)
DOI: 10.1073/pnas.0308527100
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.251120.5%1.9%7.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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