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1RU1

CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF E. COLI HPPK(V83G/DEL84-89) WITH MGAMPCPP AND 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN AT 1.40 ANGSTROM RESOLUTION (MONOCLINIC FORM)

Summary for 1RU1
Entry DOI10.2210/pdb1ru1/pdb
Related1CBK 1DY3 1EQ0 1EQM 1EX8 1F9H 1F9Y 1G4C 1HKA 1HQ2 1HQ9 1IM6 1KBR 1Q0N 1RAO 1RB0 1RTZ 1RU2
Descriptor2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, MAGNESIUM ION, CHLORIDE ION, ... (6 entities in total)
Functional Keywordspyrophosphokinase, pyrophosphoryl transfer, folate, hppk, pterin, 6-hydroxymethyl-7, 8-dihydropterin, antimicrobial agent, drug design, deletion mutant, transferase
Biological sourceEscherichia coli
Total number of polymer chains2
Total formula weight35722.41
Authors
Blaszczyk, J.,Ji, X. (deposition date: 2003-12-10, release date: 2004-02-24, Last modification date: 2023-08-30)
Primary citationBlaszczyk, J.,Li, Y.,Wu, Y.,Shi, G.,Ji, X.,Yan, H.
Essential Roles of a Dynamic Loop in the Catalysis of 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase.
Biochemistry, 43:1469-1477, 2004
Cited by
PubMed: 14769023
DOI: 10.1021/bi036053l
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.4 Å)
Structure validation

217705

건을2024-03-27부터공개중

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