1RTD

STRUCTURE OF A CATALYTIC COMPLEX OF HIV-1 REVERSE TRANSCRIPTASE: IMPLICATIONS FOR NUCLEOSIDE ANALOG DRUG RESISTANCE

1RTD の概要

• エントリーDOI: 10.2210/pdb1rtd/pdb
• 分子名称: DNA TEMPLATE FOR REVERSE TRANSCRIPTASE, DNA PRIMER FOR REVERSE TRANSCRIPTASE, PROTEIN (REVERSE TRANSCRIPTASE), ... (6 entities in total)
• 機能のキーワード: complex(nucleotidyltransferase, dna, dntp), protein/dna, transferase-dna complex, transferase/dna
• 由来する生物種: Human immunodeficiency virus 1; 詳細
• 細胞内の位置: Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03366 P04585
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 261133.52

構造登録者

Chopra, R.,Huang, H.,Verdine, G.L.,Harrison, S.C. (登録日: 1998-08-26, 公開日: 1998-12-09, 最終更新日: 2024-02-14)

• 主引用文献: Huang, H.,Chopra, R.,Verdine, G.L.,Harrison, S.C.; Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance.; Science, 282:1669-1675, 1998; PubMed: 9831551; DOI: 10.1126/science.282.5394.1669

実験手法

X-RAY DIFFRACTION (3.2 Å)