1RL4

Plasmodium falciparum peptide deformylase complex with inhibitor

Summary for 1RL4

Related1JYM
Descriptorformylmethionine deformylase, COBALT (II) ION, (2R)-2-{[FORMYL(HYDROXY)AMINO]METHYL}HEXANOIC ACID, ... (5 entities in total)
Functional Keywordscrystal engineering, drug design, malaria, pdf, peptide deformylase, plasmodium, hydrolase
Biological sourcePlasmodium falciparum
Total number of polymer chains2
Total molecular weight46429.93
Authors
Robien, M.A.,Nguyen, K.T.,Kumar, A.,Hirsh, I.,Turley, S.,Pei, D.,Hol, W.G.J. (deposition date: 2003-11-24, release date: 2003-12-09, Last modification date: 2011-07-13)
Primary citation
Robien, M.A.,Nguyen, K.T.,Kumar, A.,Hirsh, I.,Turley, S.,Pei, D.,Hol, W.G.J.
An improved crystal form of Plasmodium falciparum peptide deformylase.
Protein Sci., 13:1155-1163, 2004
PubMed: 15010544 (PDB entries with the same primary citation)
DOI: 10.1110/ps.03456404
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.18 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.22910016.5%4.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution