1R81

Glycosyltransferase A in complex with 3-amino-acceptor analog inhibitor and uridine diphosphate-N-acetyl-galactose

1R81 の概要

• エントリーDOI: 10.2210/pdb1r81/pdb
• 関連するPDBエントリー: 1R7T 1R7U 1R7V 1R7X 1R7Y 1R80 1R82
• 分子名称: Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, alpha-L-fucopyranose-(1-2)-hexyl 3-amino-3-deoxy-beta-D-galactopyranoside, MERCURY (II) ION, ... (5 entities in total)
• 機能のキーワード: glycoprotein, transmembrane, signal-anchor, blood group antigen, transferase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein: P16442
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34818.33

構造登録者

Nguyen, H.P.,Seto, N.O.L.,Cai, Y.,Leinala, E.K.,Borisova, S.N.,Palcic, M.M.,Evans, S.V. (登録日: 2003-10-22, 公開日: 2004-02-10, 最終更新日: 2022-12-21)

• 主引用文献: Nguyen, H.P.,Seto, N.O.L.,Cai, Y.,Leinala, E.K.,Borisova, S.N.,Palcic, M.M.,Evans, S.V.; The influence of an intramolecular hydrogen bond in differential recognition of inhibitory acceptor analogs by human ABO(H) blood group A and B glycosyltransferases; J.Biol.Chem., 278:49191-49195, 2003; PubMed: 12972418; DOI: 10.1074/jbc.M308770200

実験手法

X-RAY DIFFRACTION (1.75 Å)