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1R5V

Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T-cell activation

Summary for 1R5V
Entry DOI10.2210/pdb1r5v/pdb
DescriptorH-2 class II histocompatibility antigen, E-K alpha chain, artificial peptide, MHC H2-IE-beta, ... (4 entities in total)
Functional Keywordstcr, mhc class ii, structural rearangement, signaling protein
Biological sourceMus musculus (house mouse)
More
Cellular locationMembrane; Single-pass type I membrane protein (Potential): P04224 P18468
Total number of polymer chains6
Total formula weight88220.47
Authors
Krogsgaard, M.,Prado, N.,Adams, E.J.,He, X.L.,Chow, D.C.,Wilson, D.B.,Garcia, K.C.,Davis, M.M. (deposition date: 2003-10-13, release date: 2004-02-03, Last modification date: 2021-10-27)
Primary citationKrogsgaard, M.,Prado, N.,Adams, E.J.,He, X.L.,Chow, D.C.,Wilson, D.B.,Garcia, K.C.,Davis, M.M.
Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T cell activation.
Mol.Cell, 12:1367-1378, 2003
Cited by
PubMed: 14690592
DOI: 10.1016/S1097-2765(03)00474-X
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

217705

數據於2024-03-27公開中

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