1Q51

Crystal Structure of Mycobacterium tuberculosis MenB in Complex with Acetoacetyl-Coenzyme A, a Key Enzyme in Vitamin K2 Biosynthesis

Summary for 1Q51

Entry DOI	10.2210/pdb1q51/pdb
Related	1DCI 1DUB 1EF8 1HNU 1NZY 1O8U 1Q52
Descriptor	menB, ACETOACETYL-COENZYME A (3 entities in total)
Functional Keywords	lyase, structural genomics, psi, protein structure initiative, tb structural genomics consortium, tbsgc
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	12
Total formula weight	427002.54
Authors	Truglio, J.J.,Theis, K.,Feng, Y.,Gajda, R.,Machutta, C.,Tonge, P.J.,Kisker, C.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2003-08-05, release date: 2004-01-27, Last modification date: 2023-08-16)
Primary citation	Truglio, J.J.,Theis, K.,Feng, Y.,Gajda, R.,Machutta, C.,Tonge, P.J.,Kisker, C. Crystal structure of Mycobacterium tuberculosis MenB, a key enzyme in vitamin K2 biosynthesis. J.Biol.Chem., 278:42352-42360, 2003 Cited by PubMed: 12909628 DOI: 10.1074/jbc.M307399200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation