1Q3W

GSK-3 Beta complexed with Alsterpaullone

Summary for 1Q3W

Entry DOI	10.2210/pdb1q3w/pdb
Related	1PYX 1Q3D 1Q41
Descriptor	GLYCOGEN SYNTHASE KINASE-3 BETA, 9-NITRO-5,12-DIHYDRO-7H-BENZO[2,3]AZEPINO[4,5-B]INDOL-6-ONE (3 entities in total)
Functional Keywords	kinase, insulin pathway, alsterpaullone, transferase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P49841
Total number of polymer chains	2
Total formula weight	94749.50
Authors	Bertrand, J.A.,Thieffine, S.,Vulpetti, A.,Cristiani, C.,Valsasina, B.,Knapp, S.,Kalisz, H.M.,Flocco, M. (deposition date: 2003-08-01, release date: 2003-10-21, Last modification date: 2023-08-16)
Primary citation	Bertrand, J.A.,Thieffine, S.,Vulpetti, A.,Cristiani, C.,Valsasina, B.,Knapp, S.,Kalisz, H.M.,Flocco, M. Structural Characterization of the Gsk-3Beta Active Site Using Selective and Non-selective ATP-Mimetic Inhibitors J.Mol.Biol., 333:393-407, 2003 Cited by PubMed: 14529625 DOI: 10.1016/j.jmb.2003.08.031 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation