1Q1T

Mouse Importin alpha: non-phosphorylated SV40 CN peptide complex

Summary for 1Q1T

• Entry DOI: 10.2210/pdb1q1t/pdb
• Related: 1EJL 1EJY 1IAL 1PJM 1PJN
• Descriptor: Large T antigen, Importin alpha-2 subunit (3 entities in total)
• Functional Keywords: importin alpha/karyopherin alpha, nuclear localisation sequence (nls) recognition, phosphorylation, simian virus (sv40) large tumor-antigen (t-antigen) nls, x-ray crystal structure, protein transport
• Biological source: Mus musculus (house mouse); More
• Cellular location: Host nucleus: P03070 P03070
• Total number of polymer chains: 3
• Total formula weight: 55833.17

Authors

Fontes, M.R.M.,Teh, T.,Toth, G.,John, A.,Pavo, I.,Jans, D.A.,Kobe, B. (deposition date: 2003-07-22, release date: 2004-03-30, Last modification date: 2023-08-16)

• Primary citation: Fontes, M.R.M.,Teh, T.,Toth, G.,John, A.,Pavo, I.,Jans, D.A.,Kobe, B.; Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha; Biochem.J., 375:339-349, 2003; PubMed: 12852786; DOI: 10.1042/BJ20030510

Experimental method

X-RAY DIFFRACTION (2.5 Å)