1PYX

GSK-3 Beta complexed with AMP-PNP

Summary for 1PYX

Entry DOI	10.2210/pdb1pyx/pdb
Descriptor	Glycogen synthase kinase-3 beta, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (4 entities in total)
Functional Keywords	kinase, insulin pathway, transferase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P49841
Total number of polymer chains	2
Total formula weight	95020.38
Authors	Bertrand, J.A.,Thieffine, S.,Vulpetti, A.,Cristiani, C.,Valsasina, B.,Knapp, S.,Kalisz, H.M.,Flocco, M. (deposition date: 2003-07-09, release date: 2003-10-21, Last modification date: 2023-08-16)
Primary citation	Bertrand, J.A.,Thieffine, S.,Vulpetti, A.,Cristiani, C.,Valsasina, B.,Knapp, S.,Kalisz, H.M.,Flocco, M. Structural characterization of the GSK-3beta active site using selective and non-selective ATP-mimetic inhibitors J.Mol.Biol., 333:393-407, 2003 Cited by PubMed: 14529625 DOI: 10.1016/j.jmb.2003.08.031 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation