1PBD

CRYSTAL STRUCTURES OF WILD-TYPE P-HYDROXYBENZOATE HYDROXYLASE COMPLEXED WITH 4-AMINOBENZOATE, 2,4-DIHYDROXYBENZOATE AND 2-HYDROXY-4-AMINOBENZOATE AND OF THE TRY222ALA MUTANT, COMPLEXED WITH 2-HYDROXY-4-AMINOBENZOATE. EVIDENCE FOR A PROTON CHANNEL AND A NEW BINDING MODE OF THE FLAVIN RING

Summary for 1PBD

• Entry DOI: 10.2210/pdb1pbd/pdb
• Descriptor: P-HYDROXYBENZOATE HYDROXYLASE, FLAVIN-ADENINE DINUCLEOTIDE, 4-AMINOBENZOIC ACID, ... (4 entities in total)
• Functional Keywords: oxidoreductase
• Biological source: Pseudomonas fluorescens
• Total number of polymer chains: 1
• Total formula weight: 45287.19

Authors

Schreuder, H.A.,Mattevi, A.,Hol, W.G.J. (deposition date: 1994-07-06, release date: 1994-09-30, Last modification date: 2024-02-14)

• Primary citation: Schreuder, H.A.,Mattevi, A.,Obmolova, G.,Kalk, K.H.,Hol, W.G.,van der Bolt, F.J.,van Berkel, W.J.; Crystal structures of wild-type p-hydroxybenzoate hydroxylase complexed with 4-aminobenzoate,2,4-dihydroxybenzoate, and 2-hydroxy-4-aminobenzoate and of the Tyr222Ala mutant complexed with 2-hydroxy-4-aminobenzoate. Evidence for a proton channel and a new binding mode of the flavin ring; Biochemistry, 33:10161-10170, 1994; PubMed: 7520279; DOI: 10.1021/bi00199a044

Experimental method

X-RAY DIFFRACTION (2.3 Å)