1P5E

The structure of phospho-CDK2/cyclin A in complex with the inhibitor 4,5,6,7-tetrabromobenzotriazole (TBS)

Summary for 1P5E

Entry DOI	10.2210/pdb1p5e/pdb
Descriptor	Cell division protein kinase 2, Cyclin A2, 4,5,6,7-TETRABROMOBENZOTRIAZOLE, ... (4 entities in total)
Functional Keywords	kinase inhibitor, cdk2, tbs, cell cycle
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome: P24941 Nucleus : P20248
Total number of polymer chains	4
Total formula weight	128405.10
Authors	De Moliner, E.,Brown, N.R.,Johnson, L.N. (deposition date: 2003-04-26, release date: 2003-07-01, Last modification date: 2016-12-21)
Primary citation	De Moliner, E.,Brown, N.R.,Johnson, L.N. Alternative binding modes of an inhibitor to two different kinases Eur.J.Biochem., 270:1-8, 2003 Cited by PubMed: 12869192 DOI: 10.1046/j.1432-1033.2003.03697.x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.22 Å)

Structure validation