1OY0

The crystal Structure of the First Enzyme of Pantothenate Biosynthetic Pathway, Ketopantoate Hydroxymethyltransferase from Mycobacterium Tuberculosis Shows a Decameric Assembly and Terminal Helix-Swapping

1OY0 の概要

• エントリーDOI: 10.2210/pdb1oy0/pdb
• 分子名称: Ketopantoate hydroxymethyltransferase, MAGNESIUM ION (3 entities in total)
• 機能のキーワード: domain swapping, structural genomics, psi, protein structure initiative, tb structural genomics consortium, tbsgc, transferase
• 由来する生物種: Mycobacterium tuberculosis
• 細胞内の位置: Cytoplasm (Potential): P0A5Q8
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 146947.96

構造登録者

Chaudhuri, B.N.,Sawaya, M.R.,Kim, C.Y.,Waldo, G.S.,Park, M.S.,Terwilliger, T.C.,Yeates, T.O.,TB Structural Genomics Consortium (TBSGC) (登録日: 2003-04-03, 公開日: 2003-07-15, 最終更新日: 2024-02-14)

• 主引用文献: Chaudhuri, B.N.,Sawaya, M.R.,Kim, C.Y.,Waldo, G.S.,Park, M.S.,Terwilliger, T.C.,Yeates, T.O.; The Crystal Structure of the First Enzyme in the Pantothenate Biosynthetic Pathway, Ketopantoate Hydroxymethyltransferase, from M. tuberculosis; Structure, 11:753-764, 2003; PubMed: 12842039; DOI: 10.1016/S0969-2126(03)00106-0

実験手法

X-RAY DIFFRACTION (2.8 Å)