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1OHW

4-AMINOBUTYRATE-AMINOTRANSFERASE inactivated by gamma-vinyl GABA

Summary for 1OHW
Entry DOI10.2210/pdb1ohw/pdb
Related1OHV 1OHY
Descriptor4-AMINOBUTYRATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE, 4-AMINO HEXANOIC ACID, ... (5 entities in total)
Functional Keywordstransferase, plp-dependent enzyme, aminotransferase, 4- aminobutyric acid, antiepileptic drug target, vigabatrin pyridoxal phosphate, neurotransmitter degradation, mitochondrion, transit peptide
Biological sourceSUS SCROFA (PIG)
Cellular locationMitochondrion matrix: P80147
Total number of polymer chains4
Total formula weight215340.88
Authors
Storici, P.,Schirmer, T. (deposition date: 2003-06-03, release date: 2003-10-16, Last modification date: 2011-07-13)
Primary citationStorici, P.,De Biase, D.,Bossa, F.,Bruno, S.,Mozzarelli, A.,Peneff, C.,Silverman, R.,Schirmer, T.
Structures of {Gamma}-Aminobutyric Acid (Gaba) Aminotransferase, a Pyridoxal 5'-Phosphate, and [2Fe-2S] Cluster-Containing Enzyme, Complexed with {Gamma}-Ethynyl-Gaba and with the Antiepilepsy Drug Vigabatrin
J.Biol.Chem., 279:363-, 2004
Cited by
PubMed: 14534310
DOI: 10.1074/JBC.M305884200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

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