1NW4

Crystal Structure of Plasmodium falciparum Purine Nucleoside Phosphorylase in complex with ImmH and Sulfate

Summary for 1NW4

• Entry DOI: 10.2210/pdb1nw4/pdb
• Descriptor: uridine phosphorylase, putative, SULFATE ION, 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, ... (5 entities in total)
• Functional Keywords: transition state complex, transferase
• Biological source: Plasmodium falciparum
• Total number of polymer chains: 6
• Total formula weight: 187336.37

Authors

Shi, W.,Ting, L.M.,Kicska, G.A.,Lewandowicz, A.,Tyler, P.C.,Evans, G.B.,Furneaux, R.H.,Kim, K.,Almo, S.C.,Schramm, V.L. (deposition date: 2003-02-05, release date: 2004-03-16, Last modification date: 2023-09-20)

• Primary citation: Shi, W.,Ting, L.M.,Kicska, G.A.,Lewandowicz, A.,Tyler, P.C.,Evans, G.B.,Furneaux, R.H.,Kim, K.,Almo, S.C.,Schramm, V.L.; Plasmodium falciparum Purine Nucleoside Phosphorylase: CRYSTAL STRUCTURES, IMMUCILLIN INHIBITORS, AND DUAL CATALYTIC FUNCTION.; J.Biol.Chem., 279:18103-18106, 2004; PubMed: 14982926; DOI: 10.1074/jbc.C400068200

Experimental method

X-RAY DIFFRACTION (2.2 Å)