1NMM

beta-1,4-galactosyltransferase mutant Cys342Thr complex with alpha-lactalbumin and GlcNAc

Replaces:  1JN8

Summary for 1NMM

• Entry DOI: 10.2210/pdb1nmm/pdb
• Related: 1J92
• Descriptor: ALPHA-LACTALBUMIN, BETA-1,4-GALACTOSYLTRANSFERASE, CALCIUM ION, ... (6 entities in total)
• Functional Keywords: beta1, 4-galactosyltransferase, cys342thr mutation, alpha-lactalbumin complex, transferase activator-transferase complex, transferase activator/transferase
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 4
• Total formula weight: 94641.85

Authors

Ramakrishnan, B.,Shah, P.S.,Qasba, P.K. (deposition date: 2003-01-10, release date: 2003-01-21, Last modification date: 2021-10-27)

• Primary citation: Ramakrishnan, B.,Shah, P.S.,Qasba, P.K.; alpha-Lactalbumin (LA) stimulates milk beta-1,4-galactosyltransferase I (beta 4Gal-T1) to transfer glucose from UDP-glucose to N-acetylglucosamine. Crystal structure of beta 4Gal-T1 x LA complex with UDP-Glc.; J.Biol.Chem., 276:37665-37671, 2001; PubMed: 11485999; DOI: 10.1074/jbc.M102458200

Experimental method

X-RAY DIFFRACTION (2 Å)