1NI2

Structure of the active FERM domain of Ezrin

Summary for 1NI2

DescriptorEzrin (2 entities in total)
Functional Keywordsferm, keystone, ubiquitin-like domain, acyl-coa-like domain, ph/ptb-like domain, structural protein
Biological sourceHomo sapiens (human)
Cellular locationApical cell membrane ; Peripheral membrane protein ; Cytoplasmic side  P15311
Total number of polymer chains2
Total molecular weight69896.79
Authors
Smith, W.J.,Nassar, N.,Bretscher, A.P.,Cerione, R.A.,Karplus, P.A. (deposition date: 2002-12-20, release date: 2003-02-25, Last modification date: 2018-01-31)
Primary citation
Smith, W.J.,Nassar, N.,Bretscher, A.P.,Cerione, R.A.,Karplus, P.A.
Structure of the Active N-terminal Domain of Ezrin. CONFORMATIONAL AND MOBILITY CHANGES IDENTIFY KEYSTONE INTERACTIONS.
J.Biol.Chem., 278:4949-4956, 2003
PubMed: 12429733 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M210601200
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.3 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.282232.0%2.8%10.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1ni2
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Molmil generated image of 1ni2
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Molmil generated image of 1ni2
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 1ni2
no rotation
Molmil generated image of 1ni2
rotated about x axis by 90°
Molmil generated image of 1ni2
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (1ni2.pdb2.gz [54.21 KB])
Coordinate files for Biological unit (1ni2.pdb1.gz [55.12 KB])