1NE4

Crystal Structure of Rp-cAMP Binding R1a Subunit of cAMP-dependent Protein Kinase

Summary for 1NE4

Entry DOI	10.2210/pdb1ne4/pdb
Related	1CX4 1NE6 1RGS
Descriptor	cAMP-dependent protein kinase type I-alpha regulatory chain, 6-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL (3 entities in total)
Functional Keywords	camp-dependent protein kinase, r1a subunit, camp analog, rp-camp, hydrolase
Biological source	Bos taurus (cattle)
Total number of polymer chains	1
Total formula weight	32570.65
Authors	Wu, J.,Jones, J.M.,Xuong, N.H.,Taylor, S.S. (deposition date: 2002-12-10, release date: 2004-01-13, Last modification date: 2023-08-16)
Primary citation	Wu, J.,Jones, J.M.,Xuong, N.H.,Eyck, L.F.,Taylor, S.S. Crystal Structures of RIalpha Subunit of Cyclic Adenosine 5'-Monophosphate (cAMP)-Dependent Protein Kinase Complexed with (R(p))-Adenosine 3',5'-Cyclic Monophosphothioate and (S(p))-Adenosine 3',5'-Cyclic Monophosphothioate, the Phosphothioate Analogues of cAMP. Biochemistry, 43:6620-6629, 2004 Cited by PubMed: 15157095 DOI: 10.1021/bi0302503 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation