1MQ9

Crystal structure of high affinity alphaL I domain with ligand mimetic crystal contact

Summary for 1MQ9

• Entry DOI: 10.2210/pdb1mq9/pdb
• Related: 1MQ8 1MQA
• Descriptor: Integrin alpha-L, MANGANESE (II) ION (3 entities in total)
• Functional Keywords: designed disulfide bridge, rossmann fold, metal mediated protein interface, immune system
• Biological source: Homo sapiens (human)
• Cellular location: Membrane; Single-pass type I membrane protein: P20701
• Total number of polymer chains: 1
• Total formula weight: 20550.44

Authors

Shimaoka, M.,Xiao, T.,Liu, J.-H.,Yang, Y.,Dong, Y.,Jun, C.-D.,McCormack, A.,Zhang, R.,Joachimiak, A.,Takagi, J.,Wang, J.-H.,Springer, T.A. (deposition date: 2002-09-15, release date: 2003-01-14, Last modification date: 2021-10-27)

• Primary citation: Shimaoka, M.,Xiao, T.,Liu, J.-H.,Yang, Y.,Dong, Y.,Jun, C.-D.,McCormack, A.,Zhang, R.,Joachimiak, A.,Takagi, J.,Wang, J.-H.,Springer, T.A.; Structures of the aL I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation; Cell(Cambridge,Mass.), 112:99-111, 2003; PubMed: 12526797; DOI: 10.1016/S0092-8674(02)01257-6

Experimental method

X-RAY DIFFRACTION (2 Å)