1MK7

CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA

Summary for 1MK7

• Entry DOI: 10.2210/pdb1mk7/pdb
• Related: 1MIX 1MIZ 1MK9
• Descriptor: Integrin Beta3, TALIN (3 entities in total)
• Functional Keywords: focal adhesion, integrin binding, ferm domain, cytoskeleton, npxy motif, ptb domain, structural protein
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P05106; Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side: P54939
• Total number of polymer chains: 4
• Total formula weight: 47831.14

Authors

Garcia-Alvarez, B.,De Pereda, J.M.,Calderwood, D.A.,Ulmer, T.S.,Critchley, D.,Campbell, I.D.,Ginsberg, M.H.,Liddington, R.C. (deposition date: 2002-08-28, release date: 2003-01-28, Last modification date: 2011-07-13)

• Primary citation: Garcia-Alvarez, B.,De Pereda, J.M.,Calderwood, D.A.,Ulmer, T.S.,Critchley, D.,Campbell, I.D.,Ginsberg, M.H.,Liddington, R.C.; Structural Determinants of Integrin Recognition by Talin; Mol.Cell, 11:49-58, 2003; PubMed: 12535520; DOI: 10.1016/S1097-2765(02)00823-7

Experimental method

X-RAY DIFFRACTION (2.2 Å)