1M00

Rat neuronal NOS heme domain with N-butyl-N'-hydroxyguanidine bound

Summary for 1M00

• Entry DOI: 10.2210/pdb1m00/pdb
• Related: 1LZX 1LZZ
• Descriptor: Nitric-oxide synthase, ACETATE ION, ZINC ION, ... (7 entities in total)
• Functional Keywords: nitric oxide synthase, oxydoreductase, heme-enzyme, oxidoreductase
• Biological source: Rattus norvegicus (Norway rat)
• Cellular location: Cell membrane, sarcolemma; Peripheral membrane protein (By similarity): P29476
• Total number of polymer chains: 2
• Total formula weight: 99271.75

Authors

Li, H.,Shimizu, H.,Flinspach, M.,Jamal, J.,Yang, W.,Xian, M.,Cai, T.,Wen, E.Z.,Jia, Q.,Wang, P.G.,Poulos, T.L. (deposition date: 2002-06-11, release date: 2002-11-27, Last modification date: 2024-02-14)

• Primary citation: Li, H.,Shimizu, H.,Flinspach, M.,Jamal, J.,Yang, W.,Xian, M.,Cai, T.,Wen, E.Z.,Jia, Q.,Wang, P.G.,Poulos, T.L.; The Novel Binding Mode of N-Alkyl-N'-Hydroxyguanidine to Neuronal Nitric Oxide Synthase Provides Mechanistic Insights into NO Biosynthesis; Biochemistry, 41:13868-13875, 2002; PubMed: 12437343; DOI: 10.1021/bi020417c

Experimental method

X-RAY DIFFRACTION (2.05 Å)