1LVC

Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin and 2' deoxy, 3' anthraniloyl ATP

Summary for 1LVC

Entry DOI	10.2210/pdb1lvc/pdb
Related	1K90
Descriptor	calmodulin-sensitive adenylate cyclase, calmodulin, YTTERBIUM (III) ION, ... (5 entities in total)
Functional Keywords	helical domain, protein-protein complex, lyase
Biological source	Bacillus anthracis More
Total number of polymer chains	6
Total formula weight	228969.64
Authors	Shen, Y.,Lee, Y.-S.,Soelaiman, S.,Bergson, P.,Lu, D.,Chen, A.,Beckingham, K.,Grabarek, Z.,Mrksich, M.,Tang, W.-J. (deposition date: 2002-05-28, release date: 2002-12-04, Last modification date: 2024-02-14)
Primary citation	Shen, Y.,Lee, Y.-S.,Soelaiman, S.,Bergson, P.,Lu, D.,Chen, A.,Beckingham, K.,Grabarek, Z.,Mrksich, M.,Tang, W.-J. Physiological calcium concentrations regulate calmodulin binding and catalysis of adenylyl cyclase exotoxins Embo J., 21:6721-6732, 2002 Cited by PubMed: 12485993 DOI: 10.1093/emboj/cdf681 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.6 Å)

Structure validation