1LRT

CRYSTAL STRUCTURE OF TERNARY COMPLEX OF TRITRICHOMONAS FOETUS INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE: STRUCTURAL CHARACTERIZATION OF NAD+ SITE IN MICROBIAL ENZYME

Summary for 1LRT

Entry DOI	10.2210/pdb1lrt/pdb
Related	1AK5
Descriptor	INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, octyl beta-D-glucopyranoside, POTASSIUM ION, ... (7 entities in total)
Functional Keywords	ternary complex, alpha-beta barrel, flexible loop, flap, oxidoreductase
Biological source	Tritrichomonas foetus More
Cellular location	Cytoplasm : P50097
Total number of polymer chains	4
Total formula weight	171065.15
Authors	Gan, L.,Petsko, G.A.,Hedstrom, L. (deposition date: 2002-05-15, release date: 2003-07-07, Last modification date: 2020-07-29)
Primary citation	Gan, L.,Petsko, G.A.,Hedstrom, L. Crystal structure of a ternary complex of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase: NAD+ orients the active site loop for catalysis Biochemistry, 41:13309-13317, 2003 Cited by PubMed: 12403633 DOI: 10.1021/bi0203785 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation