1LCJ
SH2 (SRC HOMOLOGY-2) DOMAIN OF HUMAN P56-LCK TYROSINE KINASE COMPLEXED WITH THE 11 RESIDUE PHOSPHOTYROSYL PEPTIDE EPQPYEEIPIYL
Summary for 1LCJ
| Entry DOI | 10.2210/pdb1lcj/pdb |
| Descriptor | P56==LCK== TYROSINE KINASE, PHOSPHOPEPTIDE EPQ(PHOSPHO)YEEIPIYL (3 entities in total) |
| Functional Keywords | complex (kinase-peptide), complex (kinase-peptide) complex, complex (kinase/peptide) |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: P06239 Host membrane; Single-pass membrane protein (Potential): P03079 |
| Total number of polymer chains | 2 |
| Total formula weight | 13862.34 |
| Authors | Eck, M.,Harrison, S. (deposition date: 1994-12-12, release date: 1995-10-15, Last modification date: 2011-07-13) |
| Primary citation | Eck, M.J.,Shoelson, S.E.,Harrison, S.C. Recognition of a high-affinity phosphotyrosyl peptide by the Src homology-2 domain of p56lck. Nature, 362:87-91, 1993 Cited by PubMed: 7680435DOI: 10.1038/362087a0 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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